In 2017, CIRM funded a discovery or early stage research project for Dr. Caroline Kuo at UCLA for a hereditary immune disorder known as X-Linked Hyper IgM Syndrome. The work has gone so well that Dr. Kuo and her team are now preparing the pre-clinical work needed to launch a clinical trial. Thanks to the … Continue reading CIRM progression award to support research towards immunodeficiency

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You can’t look at this photo and not smile. This is Evie Vaccaro, and it’s clear she is just bursting with energy and vitality. Sometimes it feels like I have known Evie all her life. In a way I have. And I feel so fortunate to have done so, and that’s why this photo is … Continue reading Celebrating a life that almost didn’t happen

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Here at CIRM we only fund clinical trials that meet the rigorous standards outlined by the Food and Drug Administration (FDA). These requirements are not only necessary to properly evaluate how effective a potential treatment may be, but they are also important in fulfilling the Hippocratic Oath to “first, do no harm”. The journey from … Continue reading Unproven “stem cell” therapy injuries are more common than we realized

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While most people probably wouldn’t put 2020 in their list of favorite years, it’s certainly turning out to be a good one for jCyte. Earlier this year jCyte entered into a partnership with global ophthalmology company Santen Pharmaceuticals worth up to $252 million. Then earlier this week they announced some encouraging results from their Phase … Continue reading Encouraging news for treatment targeting retinitis pigmentosa

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This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two new discovery research project as part of the $5 million in emergency funding for COVID-19 related projects.  This brings the number of COVID-19 projects CIRM is supporting to 17, including three clinical trials. $249,974 was awarded to Dr. Karen Christman at UC … Continue reading CIRM Board Approves Two New Discovery Research Projects for COVID-19

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If someone told you they were working on lungs in a dish you might be forgiven for thinking that’s the worst idea for a new recipe you have ever heard of. But in the case of Dr. Evan Snyder and his team at Sanford Burnham Prebys Medical Discovery Institute it could be a recipe for … Continue reading Using mini lungs to test potential COVID-19 therapies

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A simple blood stem cell transplant is showing tremendous promise in treating a wide range of metabolic, blood and immune disorders such as thalassemia and some leukodystrophies. These are considered rare diseases – meaning there are fewer than 200,000 people with them in the US – so there is often little funding available to develop … Continue reading Cord blood transplants help children fighting deadly diseases

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According to the Centers for Disease Control and Prevention (CDC), heart disease is the leading cause of death for men, women, and people of most racial and ethnic groups in the United States. About 647,000 Americans die from heart disease each year, which is roughly one out of every four deaths total in the US. In order to better study … Continue reading Researchers 3D print a heart pump using stem cells

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Out of 100 couples in the US, around 12 or 13 will have trouble starting a family. In one third of those cases the problem is male infertility (one third is female infertility and the other third is a combination of factors). In the past treatment options for men were often limited. Now a new … Continue reading Lab-grown human sperm cells could unlock treatments for infertility

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This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) approved two additional discovery research projects as part of the $5 million in emergency funding for COVID-19 related projects.  This brings the number of COVID-19 projects CIRM is supporting to 15, including three clinical trials. The Board awarded $249,999 to Dr. Evan Snyder at … Continue reading CIRM Board Approves Two Discovery Research Projects for COVID-19

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